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+1-888.733.6849
+1-617.299.7367 (Int’l)
Introduction | Protein A is a cell wall protein deriving from Staphylococcus aureus which exhibits unique binding properties for IgG from a variety of mammalian species and for some IgM and IgA as well. It binds with the Fc region of immunoglobulins throµgh interaction with the heavy chain. It couples to a wide variety of reporter molecules including fluorescent dyes, enzyme markers, biotin, colloidal gold and radioactive iodine without affecting the antibody binding site. Recombinant Protein A was developed to increase the specificity of the molecule for IgG and is widely used both in research and bioprocessing. The recombinant protein A is produced by expressing a modified protein A gene in E.coli. A specific purification process with strict quality control was taken to get the recombinant protein A with the purity of more than 98% , no human IgG affinity step is used during validated fermentation and purification and devoid of bacterial contaminant found normally in native Protein A. (Free of Staphylococcus endotoxins and hemolysin). |
Synonyms | Immunoglobulin G-binding protein A, IgG-binding protein A, Staphylococcal protein A, SPA. |
Source | Escherichia Coli. |
Physical Appearance | Sterile Filtered clear colorless solution. |
Formulation | The protein solution contains no additives. |
Stability | SPA should be stored at -20°C. |
Purity | Greater than 98.0% as determined by RP-HPLC. |
Biological Activity | Greater than 95.0% binding activity to human IgG. |
Usage | NeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals. |
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