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- SPECIFICATION
- BACKGROUND
- DOCUMENTS
- REVIEW
ADDITIONAL INFORMATION
SYNONYMS
DUBA8; OTUD2; PRO0907; YOD1
REACTIVITY
Human,Mouse,Rat
TESTED APPLICATIONS
ELISA,WB
RECOMMENDED DILUTION
WB,1:1000 - 1:5000
CALCULATED MW
38kDa
OBSERVED MW
38kDa
IMMUNOGEN
A synthetic peptide corresponding to a sequence within amino acids 249-348 of human YOD1(NP_061036.3).
POSITIVE SAMPLES
K-562,HEL,Mouse brain,Rat spleen
CELLULAR LOCALIZATION
cytoplasm,cytosol
STORAGE BUFFER
Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
BACKGROUND
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. The protein encoded by this gene belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain. Alternative splicing results in multiple transcript variants.
REVIEW
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