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HDAC2 Rabbit mAb

Quantity
Quantity
$148.00
  • Catalog # A19626
  • Host species Rabbit
  • Gene ID 3066
  • Purification Affinity purification
  • Swiss Prot Q92769
  • Isotype IgG
  • SPECIFICATION
  • BACKGROUND
  • DOCUMENTS
  • REVIEW

ADDITIONAL INFORMATION

SYNONYMS

HD2; RPD3; YAF1; KDAC2; HDAC2

REACTIVITY

Human,Mouse,Rat

TESTED APPLICATIONS

ELISA,WB,IP

RECOMMENDED DILUTION

WB,1:500 - 1:1000|IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells

CALCULATED MW

55kDa

OBSERVED MW

60kDa

IMMUNOGEN

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HDAC2 (NP_001518.3).

POSITIVE SAMPLES

HeLa,293T,NIH/3T3,C6,Mouse liver

CELLULAR LOCALIZATION

Cytoplasm,Nucleus,

STORAGE BUFFER

Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

BACKGROUND

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.

DOCUMENTS

REVIEW

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